10 Credits AUTUMN

Pre-requisites: BMS242, BMS243


Aims/Description: This module examines some of the key technologies that underpin modern biomedical research. Over the course of the module we will follow the development of a hypothetical antibody-based anti-cancer treatment through discovery, development and clinical trials. Teaching will be via a combination of lectures and site visits to local facilities. Led by experts in these technologies, site visits will demonstrate the application of cutting edge biomedical technologies at first hand. The aim is for students to gain a fundamental understanding of the biology, chemistry and physics that underlies some of the key techniques in modern biomedical research.This module will examine the steps involved in the development of a hypothetical new antibody- based treatment for malignant melanoma. This `bottom up' approach will be used as a framework from which to examine some of the technologies underlying modern biomedical science. Each of these key technologies will be studied at the level of the physics, chemistry and biology involved so as to gain a fundamental insight into how they work, what they can do and what their limitations might be.The course will begin by examining gene discovery approaches involving the use of next generation sequencing which could be used to identify genes whose expression is up regulated in tumours. High throughput screening of RNAi libraries will then be examined as a means of phenotypic / functional screening for gene validation.

Restrictions on availability: Due to restrictions on space in facilities to be visited a maximum of 30 students can be accommodated in Year 1 (to be reviewed before Year 2 based on experience).

Teaching Methods: Lectures, Laboratory work, Independent Study
Assessment: Course work

Information on the department responsible for this unit (Biomedical Science):

Departmental Home Page
Teaching timetable


The content of our courses is reviewed annually to make sure it's up-to-date and relevant. Individual modules are occasionally updated or withdrawn. This is in response to discoveries through our world-leading research; funding changes; professional accreditation requirements; student or employer feedback; outcomes of reviews; and variations in staff or student numbers. In the event of any change we'll consult and inform students in good time and take reasonable steps to minimise disruption.

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Teaching methods and assessment displayed on this page are indicative for 2021-22. Students will be informed by the academic department of any changes made necessary by the ongoing pandemic.

Western Bank, Sheffield, S10 2TN, UK