10 Credits SPRING

Aims/Description: The unit will provide lectures on traditional receptor theory and practical classes giving experience of isolated tissue responses and data analysis, interpretation and presentation. Common techniques employed by the pharmaceutical industry will be used to generate data from isolated living tissues. In problem-solving sessions students will be shown how to enter and manipulate the data in relevant software in order to determine drug affinities, potency and intrinsic activities. Group discussions will bring together all the class data to allow conclusions to be made about the receptor populations being studied. Numbers will be limited for this practical module.Introductory briefings will cover the theory of drug-receptor interactions, drug dilutions and bath concentrations. Students will then perform a practical class providing experience of using isolated tissues and the recording system.Following further group sessions on data manipulation and analysis, more complex practical classes will examine various concepts of receptor theory and mechanisms of neurotransmission. At each stage additional group sessions will allow data analysis, the bringing together of class results that will allow discussion and conclusions that can be justified by the results.

Teaching Methods: Tutorials, Laboratory work, Independent Study
Assessment: Course work, Practical skills assessment

Information on the department responsible for this unit (Biomedical Science):

Departmental Home Page
Teaching timetable


The content of our courses is reviewed annually to make sure it's up-to-date and relevant. Individual modules are occasionally updated or withdrawn. This is in response to discoveries through our world-leading research; funding changes; professional accreditation requirements; student or employer feedback; outcomes of reviews; and variations in staff or student numbers. In the event of any change we'll consult and inform students in good time and take reasonable steps to minimise disruption.

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Teaching methods and assessment displayed on this page are indicative for 2021-22. Students will be informed by the academic department of any changes made necessary by the ongoing pandemic.

Western Bank, Sheffield, S10 2TN, UK