Aims/Description: This is the introductory module for the MSc in Genomic Medicine and it provides the student with an introduction to the key areas of genomics and human genetics, from the structure of a gene through to how genetic variation effects phenotype. It will prepare participants to understand disease genetics and how genomic medicine can be utilised to elucidate disease mechanisms and biology. In addition this module will cover DNA sequence variation and how variation is structured across the genome explaining the principles of linkage disequilibrium and its extent in human populations (e.g. HapMap project). Students will also cover aspects of gene regulation and chromatin structure and understand the importance of genotype to phenotype correlation

Staff Contact: Helen Hickson
Teaching Methods: As a fundamental module, which introduces the basic concepts essential for the rest of the course, the key information (learning outcomes 1-6) will be provided in a series of lectures. Lectures will be supported by tutorials which will allow for discussions to introduce how genomic data will be handled in the NHS, in terms of ethics, governance and patient confidentiality (learning outcomes 7-9).
Assessment: Course work

Information on the department responsible for this unit (Neuroscience):

Teaching timetable


The content of our courses is reviewed annually to make sure it's up-to-date and relevant. Individual modules are occasionally updated or withdrawn. This is in response to discoveries through our world-leading research; funding changes; professional accreditation requirements; student or employer feedback; outcomes of reviews; and variations in staff or student numbers. In the event of any change we'll consult and inform students in good time and take reasonable steps to minimise disruption.

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Teaching methods and assessment displayed on this page are indicative for 2021-22. Students will be informed by the academic department of any changes made necessary by the ongoing pandemic.

Western Bank, Sheffield, S10 2TN, UK