10 Credits AUTUMN

Pre-requisites: MBB266

Aims/Description: The module aims to describe the methods used in the study of biological molecules, concentrating on the methods used to obtain structural information. Students will have an opportunity to acquire knowledge of the following: spectroscopy (UV/visible spectroscopy, fluorescence spectroscopy, circular dichroism spectroscopy, infra-red spectroscopy, and the applications and limits of each of these techniques in biological systems); methods for looking at protein size and aggregation; the techniques and basic principles of NMR spectroscopy, of protein crystallography, and of electron microscopy, and electron diffraction; the structural information that these techniques reveal; structural restraints, electron density, protein conformation and protein flexibility. The course will focus on the application of these techniques to selected case studies.

Staff Contact: Dr P J Baker
Teaching Methods: Lectures, Independent Study
Assessment: Formal Exam
WebCT resources are available for this module

Information on the department responsible for this unit (Molecular Biology and Biotechnology):

Departmental Home Page
Teaching timetable


The content of our courses is reviewed annually to make sure it's up-to-date and relevant. Individual modules are occasionally updated or withdrawn. This is in response to discoveries through our world-leading research; funding changes; professional accreditation requirements; student or employer feedback; outcomes of reviews; and variations in staff or student numbers. In the event of any change we'll consult and inform students in good time and take reasonable steps to minimise disruption.

URLs used in these pages are subject to year-on-year change. For this reason we recommend that you do not bookmark these pages or set them as favourites.

Teaching methods and assessment displayed on this page are indicative for 2021-22. Students will be informed by the academic department of any changes made necessary by the ongoing pandemic.

Western Bank, Sheffield, S10 2TN, UK