10 Credits SPRING

Pre-requisites: MBB261

Aims/Description: The ability of proteins to act in a dynamic manner is one of the fundamental requirements for cells to function. In this module we will cover the molecular motors myosin, kinesin and dynein: the tracks they run on (actin and microtubules); how they promote motion; how ATP is used to generate directional movement; and specific functions such as muscle contraction and cytokinesis. We then dissect in detail a complex example of a protein in action, namely the enzyme dihydrofolate reductase, looking at ligand binding and conformational exchanges, together with the techniques to analyse these changes by observing both single molecule and ensemble properties.

Staff Contact: Dr P J Baker
Teaching Methods: Lectures, Independent Study
Assessment: Formal Exam, Course work
WebCT resources are available for this module

Information on the department responsible for this unit (Molecular Biology and Biotechnology):

Departmental Home Page
Teaching timetable


The content of our courses is reviewed annually to make sure it's up-to-date and relevant. Individual modules are occasionally updated or withdrawn. This is in response to discoveries through our world-leading research; funding changes; professional accreditation requirements; student or employer feedback; outcomes of reviews; and variations in staff or student numbers. In the event of any change we'll consult and inform students in good time and take reasonable steps to minimise disruption.

URLs used in these pages are subject to year-on-year change. For this reason we recommend that you do not bookmark these pages or set them as favourites.

Teaching methods and assessment displayed on this page are indicative for 2021-22. Students will be informed by the academic department of any changes made necessary by the ongoing pandemic.

Western Bank, Sheffield, S10 2TN, UK